Sperm of infertile men is healthy when taken directly from testicles

New Delhi, Mar 17 (ANI): Scientists have found that the DNA of sperm taken from the testicles of infertile men was as good as that of ejaculated sperm of fertile men. The research may explain a major cause of male infertility and open up the possibility of using sperm taken directly from the testicles to overcome infertility among males. The research was presented at the European Association of Urology Congress in Barcelona. UK-based scientists took sperm samples from the testicles of 63 infertile men and matched them with ejaculated sperm samples produced by the same men. These infertile men had failed previous fertility treatment (intracytoplasmic sperm injection or ICSI). The scientists also examined the sperm for two types of DNA strand breaks (single and double strand breaks) each in the testicular and ejaculated sperm. Infertility is a major public health issue. One couple in six is infertile across Europe, with male infertility now being the biggest cause in couples seeking treatment. Sperm DNA damage is known to be a major cause of male infertility and reduces a couple’s chances of having a family. This study shows that on the journey from the testicles along the long series of ducts before ejaculation, sperm DNA can suffer major damage, some of which is due to oxidative stress.
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