Parter Syndrome: Causes, Symptoms and Treatment

Bartter syndrome sponsored by the compatibility of Parter is a rare syndrome described by Frederic Bartter and his colleagues from the United States 40 years ago, and contains a special combination of metabolic acidosis, low -degree chlorine in the blood (hypocalemia), and a decrease in potassium hyperemia. In a subgroup of exchange trading syndrome, called Gitelman Syndrome, the disease appears in the late childhood, or young adults where there is a low concentration of magnesium, and although the syndrome is very rare, not that the condition of a lack of potassium and chlorine with the presence of metabolic acids, or in different medical conditions, is as: as: -Trail diuretics, especially drugs from the Thiazide family and urine -diuretics. Symptoms of parter syndrome The symptoms vary with age. One of the most prominent symptoms of Parter syndrome is the following: 1. Part -Syndrome General Syndrome is one of the most prominent symptoms of Parter syndrome as follows: constipation. The urgent need to urinate. General feeling of fatigue. These are muscles. Inspiration of salt. Serious thirst. Slow growth. 2. Symptoms of larger syndrome that affect children are one of the most prominent symptoms that distinguish newborn children. The following: the dangerous temperature. Dehydration. Vomiting and diarrhea. Unusual facial features, such as: a triangular face, a big forehead and big pointed ears. Lack of natural growth. Design at birth. Other benefits of the syndrome also include sound or low blood pressure, despite the presence of large amounts of renin, aldosterone and intensive production of prostaglandins of the college. The disease is likely to appear in the uterus with an intense fetal urination state and the excess of the Amowy fluid, which can lead to premature birth. In other cases, the disease appears in the first year or two years of life with the failure to grow (fail to thrive – FTT), and an unsuccessful body temperature. The causes and facts of the risk of Parter syndrome have been concluded that the characteristic cause of Bartter syndrome can result from a basic imbalance in the periodic recording of chlorine and sodium in the rising and thick part of Henle’s loop in college, and this theory is appropriate in this part of the nephew. Over the past few years, several reports have described at least five genes responsible for coding sodium channels, potassium or chlorine, and a boom in these genes leads to the rise of barter syndrome. One of these genes is always accompanied by sensorins deafness. It has been concluded that the gene causes the disease, by a sub -unit of the chlorine channel is extensively symbolized in the brooms of the kidney and the inner ear, and that they are members in which an intense recording and secretion of ions. The risk groups have not yet been learned. Parter syndrome complications cause parter syndrome to the following complications: dehydration and constipation due to the lack of salts in the body. Weak bones, and the gravel in the kidneys is due to a decrease in calcium in the blood. Muscle weakness and cramps and severe fatigue due to potassium deficiency in the blood. Diagnosis of parter syndrome The disease is diagnosed after the signs on the patient have been observed, in addition to the following tests: A blood test: To know the concentrations of salts, such as: Calcium and potassium in the blood, in addition to measuring the degree of blood pH. Urine examination: To find out the concentration of salts in the urine. Genetic examination: A sample of the blood is taken to analyze it and ensure that there is a genetic mutation in the patient to diagnose the disease. The treatment of parter syndrome should treat different barter syndrome to pay attention to the treatment of disorders in salts, and this is initially done by adding it to food or in the image of tablets. Treatment is done by following the following procedures: Indomethacin: Andomethain is an anti -inflammatory drug that helps the body reduce the release of urine. Potassium pair diuretics: It helps with a balancing potassium in the body. RAAS -brakes: It helps prevent potassium from offering outside the body. Dietary supplements: Potassium, calcium or magnesium can be added to the patient in the form of nutritional supplements. A specific diet: rich in salts, potassium and calcium. Venous fluids: It is used in babies and very serious cases. It is noteworthy that barter syndrome is not cured, and the patient must take the necessary treatments and supplements needed during age. Prevention of barter syndrome because the cause of the Parter Jenny syndrome, and studies have not been proven by the factors it causes, there are no ways to prevent the disease.