It can be used to prevent pregnancy. Creating one injection whose effect lasts years

Researchers from the Massachusetts Institute of Technology (MIT) have developed a new way to connect medicines to higher doses and less pain by injecting it into the form of accurate crystals. As soon as they enter the skin, these crystals collect to form a “warehouse” that can take months or even years, eliminating the need for regular injection. This method can be useful for connecting long -term contraceptives, or other medications to be given for long periods. According to the study published in the journal “Nature Campical Innins”, the new method depends on the injection of medication in the form of accurate crystals hanging in an organic fluid. Once the injection, collect these crystals under the skin to form a drug warehouse that slowly releases the drug over a long period of time. This product can be given by a thin needle, making it less painful and easier to endure patients. “We have shown that we can reach sustainable and controlled delivery at the middle, perhaps for a few months or even years, through a small needle,” said the lead author of the study, Giovanni Traversu, associate professor of mechanical engineering at the Massachusetts Institute of Technology. The method depends on the suspension of the medicine crystals in an organic solvent called Benzil Benzawy, which is an important compatible substance previously used as an addition in injection used in injection. “Pharmaceutical warehouse” and at the injection causes the solvent crystals to form a pharmaceutical warehouse. The density of this warehouse can be adjusted by adding small amounts of biological analysis polymer such as Polly Cabrolctone, which can be released from the drug. “By adding a very small amount of polymers (less than 1.6% for weight), we can adjust the release rate of the drug, which extends its efficiency while maintaining the ease of injections,” says Sanjeun Park, a graduate student at the Massachusetts Institute. The researchers tested the method by spraying the subcutaneous product into the mice and showed that the pharmaceutical warehouses could remain stable, and that the drug is gradually released for three months. After the study ended, about 85% of the drug was still present in warehouses, which is an indication of the possibility of releasing the drug for a longer period. “We expect warehouses to continue for more than a year based on our initial analysis of the pre -clinical data. Subsequent studies are underway to confirm its effectiveness more,” he added. Immediately after the formation of medicine pack houses, it is sufficiently compressed that allows it to be surgically detected if necessary to stop the treatment before the medicine is completely released. Researchers are currently evaluating the possibility of applying this technique to people by conducting advanced clinical studies to assess the gas collection in a clinical more convenient learning environment. The researchers say that this system is very simple, and it consists mainly of a solvent and medicine, with the possibility of adding a small amount of biological analysis polymers: “Now we think of the applications we can target: Are these contraceptives? Or other cases?