Study: Air pollution affects the success of artificial enrichment

In a recent study, irrefutable evidence is that air pollution is linked to a low success of artificial enrichment, and this reduces the possibility of a child’s vibrant IVF, or fully recovery. The study, which was published during the introductory activities of the 40th annual meeting of the European Association of Embryology, said that exposure to fine particles greatly affected the rate of success of fertilizer in the laboratory. Scientists do not know exactly the relationship between low rate of artificial enrichment and air pollution. Oxidic tension, but it is possible that the mechanism inherent in the low rate of success of artificial fertilization due to exposure to micro parties, oxidative stress and inflammation involves. And oxidative tension, the imbalance is between the levels of antioxidants and free electrolyte levels (individual and free electrons turning into the wheat or molecular deck space). Microbial particles can enter the breathing system and enter the bloodstream, leading to physical inflammation and oxidative tension, and these conditions can disrupt the hormonal balances and weaken the function of the ovary, which is extremely important for the development and quality of eggs. In addition, inflammation can negatively affect the endometrium environment, reducing it less for embryo cultivation and thus reducing the chances of bringing living birth. The study indicates that exposure to these particles before extracting eggs can reduce the possibility of the birth of a living child by about 40%. The researchers believe that the treatment of air quality is not only essential for public health, but also to improve the results of aid -productive techniques. Microbial particles and focus on exposure to PM10 particles in the previous two weeks to extract eggs. The PM10 is particles with a diameter of 10 micrometer or less, and they are small enough to penetrate the breathing system and enter the bloodstream. These particles are released by vehicles, industrial operations and other air pollution sources. The upper exposure limit ranges from 18.63 to 35.42 micrograms per cubic meter air, while the minimum ranges from 7.08 to 12.92 microgram particles per cubic meter air. The research was conducted over the course of 8 years in the city of Perth in Australia, where 3659 frozen fetuses of 1836 women were analyzed, and the average age of women was 34.5 years at the time of the withdrawal of egg and 36.1 years at the time of transferring frozen embryos. The study examined air pollutants during 4 exposure periods of exposure before eggs were extracted as follows: “24 hours, two weeks, 4 weeks and 3 months.” Increased exposure to fine particles, with a diameter of less than 2.5 ومر M (PM2.5) in the three months before the extraction of eggs, was also associated with a decrease in the possibility of living births. Eggs have evolved and despite the excellent general air quality in this Australian city during the study period, the PM10 and PM2.5 levels exceeded 0.4% and 4.5% of the studies respectively. The lead author of the study Sebastian Levsic says that this research is the first of its kind and which uses frozen embryos to analyze the effects of exposure to pollution separately during the development of eggs, and to soon transport embryos and early pregnancy to determine whether pollution has an effect on the eggs, or on the early stages of pregnancy. The results show that the existence of a negative linear relationship between exposure to the physical materials during the two weeks, the three months that delegated the collection of eggs and the rate of living births of these eggs. This link is independent of air quality at the time of transportation of frozen embryos, and these results indicate that pollution negatively affects the quality of the eggs, and not just in the early stages of pregnancy, a discrimination that has not been reported before. External air pollution is one of the largest environmental risks for health, and the World Health Organization estimates that it causes more than 4 million early deaths around the world annually. Exposure to microscopic particles is related to a set of harmful health conditions, including heart disease, blood vessels and respiratory system. A negative relationship, and in 2021, 97% of the population of urban areas of the European Union of PM2.5 concentrations were exposed to the annual Guidelines of the World Health Organization, which amounts to 5 micrograms per cubic meter. Although data shows a clear relationship between pollution and poor reproductive results, the mechanisms that cause this problem are still unclear. “Even in the parts of the world that have extraordinary air quality, because it is acceptable for a few days for a few days, there is a strong negative connection between the amount of air pollution and the life time in frozen embryos.” He pointed out that reducing exposure to pollutants should become a major priority for public health.

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