Inflammation of the first bile ducts ... symptoms, causes and treatment
Inflammation of the initial bile ducts is an auto -immune disease that causes inflammation in the bile duct and is slowly damaged. It was previously known as the first gallgal. The yellow material is a liquid secreted in the liver that supports the digestion, and helps to absorb vitamins. It also helps the body take up fat and get rid of cholesterol, toxins and damaged red blood cells. Chronic hepatitis can lead to inflammation and damage in bile ducts while inflammation of bile ducts. Sometimes it can cause a permanent scar in the tissue of the liver called cirrhosis. This can eventually lead to liver failure. Although inflammation in bile ducts affects both sexes, it affects women in most cases. Galk channel inflammation is one of the auto -immune diseases, that is, it drives the body’s immune system to accidentally attack healthy cells and tissues. The researchers believe that there is a group of genetic and environmental factors that have a role in this disease. The stages of this disease usually develop slowly. Although there is currently no cure for the inflammation of the first bile ducts, the medicine can delay the liver damage, especially if the treatment begins early. Symptoms of the first bile tube inflammation do not feel more than half of the patients of primary gal inflammation, with any noticeable symptoms when diagnosed. The disease can be discovered in carrying out blood tests for other reasons, such as routine tests. The symptoms then develop within a period of 5 years to 20 years. For people who have symptoms after diagnosis, their results are usually worse. Common early symptoms include the following: Fatigue. Itching in the skin. The symptoms and indicators for late diseases may include: yellowing of the skin and eyes (Chrosan). Dry eyes and mouth. Pain in the upper right of the abdomen. The spleen is reinforced. Leg pain, joints or muscles. Foot swelling and ankles. The accumulation of fluid in the abdomen due to the failure of the liver (dropy). Octicides (called the yellow tumor) on the skin and around the eye and eyelids, or in the folds of the palm of the hand, the soles, the elbows or knees. The darkening of the skin without exposure to the sun is called hyperpigmentation. Bone weakness and thinner (osteoporosis) to some extent that can lead to fractions. High cholesterol level. Diarrhea, which may include fatty stools, is called fatty diarrhea. Hypothyroidism is called thyroid insufficiency. Weight loss. The causes of the first bilexic inflammation are not a clear cause of the infection of the first bile ducts. Many specialists consider it a disease of auto -immune, in which the body attacks itself. Researchers also believe that this auto mune response can be stimulated by environmental and genetic factors. Hepatitis caused by the first gala channel inflammation, appearing when certain types of white blood cells begin, called T -cells (or T -lipphocytes), in the collection in the liver. In normal conditions, these immune cells monitor germs, bacteria and viruses and help prevent them. But in the case of inflammation of the first bile ducts, they accidentally attack healthy cells that put the small gallbladder channels in the liver. Inflammation spreads in the smaller channels to eventually destroy other cells in the liver. With the death of cells, it is replaced by scar tissue, which is also known as fibers, which can lead to cirrhosis. And was a scar in the liver tissue leading to violating the liver’s ability to work normally. Diagnosis The following tests and procedures for the diagnosis of the first bile duct inflammation can be done. Blood tests: Liver tests. These blood tests determine certain proteins that may indicate liver disease and sorials channels. Anti -Antiligga tests for auto -immune diseases. Blood tests can also be performed to detect the presence of antibacterial antibodies. These substances are almost completely absent in those with people with the disease, even if they have other problems in the liver. Therefore, the positive results of the antibody tests of the anti -Mitochondria are one of the conclusive signs that indicate the disease. However, there are no anti -mitochondria antibodies in a number of first bile tube inflammation. Cholesterol test. More than half of the patients of the first bile duct inflammation suffer from a high level of fat in the blood, including the total cholesterol level. The image tests will help the healthcare team to verify a diagnosis or exclude other patients involving similar signs and symptoms. Liver and gala channel tests may include: ultrasound. Ultrasound tests use high frequency sound waves to photograph the organs in your body. Vibroskan exam. Through this test, liver chips can be discovered using a sin that makes ultrasound frequencies. Photography of the Sorching and Sorching Sorch in MRI. This special examination, conducted with MRI, takes detailed images of the body and bile ducts. MRI bending combines this investigation between magnetic resonance imaging and sound waves to draw a visual map of the internal organs called elastogram. This investigation is used to detect liver hardening, which may indicate that it has a helicopter. The doctor can use the liver biopsy if he does not reach a definitive diagnosis after previous tests. A small sample of the liver tissue is taken in this procedure using a thin needle through a small incision. The sample is then subject to the laboratory examination, to confirm the diagnosis or determine the extent of the disease. The treatment of the first bilexic inflammation. Treatment of the disease. There is no healing treatment for the inflammation of the first bile, but medication can slow down the disease and prevent complications. The options include the following: Ursodixicolic Acid is used by this medicine, also known as the Actigall and Urso, often at the beginning of treatment. It helps to transfer the gallack juice over the liver. However, Ursodixicic Acid does not cure the first gallonitis, despite its apparent impact on improving the liver function and reducing liver scar. It is unlikely to help reduce itching and feeling tired. Possible side effects include weight gain, dizziness, hair loss and diarrhea. Ocaliva acid shows studies that eating open -colic acid alone or with ursodiol can contribute to the improvement of liver function and slowing down the tissue of its tissues. But it is often used in a limited range as it can lead to increased itching. Vibrat (Tricor) researchers weren’t sure how these medicines work to relieve symptoms associated with primary gal inflammation. But if eaten with ursodixicolic acid orsodioxicolic, it reduces hepatitis and itching in some patients. More studies are needed to determine the desired benefits in the long run. Bodesonide can be to take body soda, which is a type of corticosteroid, with ursodixicicolic acid, potential benefits in the treatment of primary bile duct inflammation. Nevertheless, the intake of this drug is associated with the occurrence of side effects associated with the steroids for those who have reached the late stages of the disease. Therefore, it is necessary to perform more long -term experiments before the possibility of recommending the medicine of body monids to treat this condition. Liver transplantation, in the event that medication is not useful for treating the first bile inflammation and the beginning of the liver failure, the liver cultivation can give the patient the opportunity to extend his life. In the cultivation of the liver, the liver is replaced by a healthy one of one of the donors. The results of liver transplants in people with primary gal inflammation are very good and long. But the disease can return to a few years of liver transplantation. The treatment of symptoms may recommend the healthcare team with treatments to control the indicators and symptoms of the first inflammation of the bile duct and give the patient greater ease. Ride C Totalization causes the inflammation of the first bile ducts. But you can be influenced by feeling tired of your daily habits, proper diet, exercise and other diseases. It is also important to take a test to exclude thyroid disease; Because it occurs more frequently for those with inflammation of the first bile ducts. Itch treatment is common to use antihistamines to reduce itching and can help sleep if itching occurs your sleep. It contains antihistamine dipheninamine, hydroxycine hydrochloride and leuradine. Colesmanine powder can stop the itching, and it should be mixed with food or fluids. Riverbin is an antibiotic that can stop the itch, but the way it works is not exactly known. The researchers believe that this can prevent the brain’s reaction to itchingchemicals in the blood. Anti -actual antibiotics such as those containing naluxone and nalc zone can help relieve the itching caused by liver disease. As the case with rifampine, this medication seems to reduce the feeling of itching by affecting the brain. Certraline is a drug that increases serotonin in the brain, which is a selective serotoninreeum (SSRI), and it can help reduce the feeling of itching. The treatment of dry eyes and mouths can help artificial tears or salivary alternatives reduce dry eyes and mouth. It can be obtained with or without prescription. Chewing gum or absorption of solid dessert also helps to secrete more saliva and relieve dry mouth. The treatment of complications. Certain complications are related to the primary bile duct inflammation. The healthcare team may recommend the following: Metal and vitamin supplements. If the body does not absorb vitamins or other nutrients, the patient may need to take vitamins A, D, E and K. It may also take calcium, folic acid or iron supplements. Cholesterol lower medication. The healthcare team may recommend taking a drug known as static to reduce cholesterol if the patient has a high level of cholesterol in the blood. Bone density loss medication. Medicines and supplements such as calcium and vitamin D can be prescribed to reduce bone loss and improve their density if you are patient with a weak bone, or her osteoporosis. Exercise, such as walking and lifting lightweights most of the week, can increase the bone density. The treatment of increased pressure within the portal called portal hypertension. The healthcare team is likely to examine the patient and follow his condition to see if he has a portal hypertension or enlarged veins, if it has scars of liver disease. The presence of a liquid in the abdomen is one of the common side effects of portal hypertension. In cases of minor accumulation of fluid, the healthcare team can only recommend reducing salt in the diet. In the most serious cases, it may be necessary to take medication known as diuretics or the implementation of a fluid drainage procedure called the puncture. *This content of “Mayo Clinic”