Chronic mystery leukemia: symptoms, causes and treatment
Chronic myelocytic leukemia sponsored by chronic stuffed leukemia is the disease in which the stem cell in the bone marrow from which all blood cells develop becomes a cancerous cell, which usually occurs elderly and rarely occurs in children, although it can occur at any age. The majority of patients are diagnosed in the chronic stage of the disease, where the disease is discovered at 20% – 30% of patients by chance, and when we perform a comprehensive routine blood test, we see the large number of white blood cells in the blood. Symptoms of chronic papleucia are clinical manifestations of chronic disgusting leukemia and change some with the progress of the disease. Patients in chronic stage may be without symptoms, or they may show one of the following signs and symptoms: fatigue. Weight loss. Energy loss. Reduced exercise. Low -class fever. Excessive sweating of metabolism. The large number of white blood cells. Early saturation and low eating. The left upper quarter of the abdominal pain caused by Miltinfarkt. Liver enlargement. bleeding. Bruises during the accelerated stage. Leg pain. Increased anemia. Causes and factors of the risk of chronic myelling leukemia in the following are an exposition of the most prominent causes and risk factors: 1. Causes of chronic myelleukemia include the most important causes of the following: the development of abnormal chromosome. Human cells usually contain 23 pairs of chromosomes, as these chromosomes contain DNA containing genes that control the division and development of body cells. In people with chronic pyramid leukemia, chromosomes exchange portions in the blood cells, where there are part of the switches of chromosome 9 with a cut of chromosome 22, leading to the creation of a very short 22 chromosome and a very long chromosome. The 22 short chromosome is called the Philadelphia chromosome, named after the city in which it was discovered, where the Philadelphia chromosome in the blood cells of the infected was infected by 90% of the chronic myel. An abnormal chromosome builds a new gene that the Philadelphia chromosome builds a new gene, where genes of the 9 chromosome are united with gene of chromosome 22 to create a new gene called BCR-IAB, where the BCR-IAB gene instructions that have abnormal blood cells of the production of a lot of protein (tyrosin (tyrosine) Inform the enzyme by growing cancer by growing certain blood cells beyond the extent of the control. To perform more tests. A needle is used to remove a small sample from the bone marrow. You may experience some discomfort during the procedure, but it should not be painful. The process usually lasts about 15 minutes and usually does not have to stay in the hospital all night. You may experience bruises and discomfort a few days afterwards. The bone marrow will be investigated in search of cancer cells and cells will be analyzed to determine your type of leukemia and its progress. This can help your doctors determine the best treatment for you. The treatment of chronic porridge leukemia is the purpose of treating chronic mystery leukemia is to eliminate blood cells that contain an abnormal BCR-AAB gene that causes an abundance of diseased blood cells, and for most people the treatment of directed medicines that can help to effect long-term stability of the disease, and the prominent methods of the silk are the next. enable to grow and reproduce, in chronic myelling blood leukemia, the purpose of this medicine is the protein produced by the BCRAP. The targeted medicine that prevents the operation of Turzin Kiniz includes the following: Imatinib. Dasatinib. Nilotinib. Bosutinib. Ponatinib. Provided medicine The initial treatment is from people with chronic myelleicemia, and the side effects of this targeted medication include swelling or swelling of the skin, nausea, muscle spasms, fatigue, diarrhea and rash. Doctors have not specified a safe point that people with chronic myelling blood leukemia can stop taking targeted medication, for this reason most people continue to take targeted medication, even if blood tests look calm, and in some cases you and your doctor may consider stopping the treatment with purposeful medication after thinking before the benefits and risks. 2. Bone marrow transplant is the bone marrow transplant, which is also called stem cell transplantation. The only opportunity for a final treatment for chronic myelle leukemia, but it is usually intended for people who have not been assisted by other treatments; Because bone marrow transplants pose risks and have a high rate of serious complications. During bone marrow transplantation, high doses of chemotherapy medicine are used to kill blood bone marrow cells. Subsequently, stem blood cells of the donor are pumped into the bloodstream and new cells form new and healthy blood cells to replace sick cells. 3. Chemotherapy Chemotherapy is a drug therapy that kills rapid growing cells in the body, including leukemia cells, and sometimes chemotherapy medication and drug therapy aimed at treating aggressive chronic lean blood, and the side effects of chemotherapy medicine depend on the medicine you take. Prevention of chronic myelleukemia cannot prevent the disease.