A glitter of hope for Parkinson patients

Two small studies published by the “Nature” Scientific Journal in April offer an important initial assertion on the feasibility of a treatment for Parkinson disease based on stem cells. It is also two steps towards a future in which stem cells can be used not only for treatment, but to restore or prevent brain damage in perfect condition. It requires accurate coordination and an ongoing dedication to understand the causes of degenerative neurological diseases so that we cannot correct what we do not realize that it is damaged. These two drugs, one of which originally developed a team from the “Memorial Celed Citrring” Cancer Center in New York and the other researchers in Kyoto, Japan, is the highlight of decades of work to discover how to transform stem cells into functional treatments for Parkinson’s disease. (To make it clear, these stem cells are designed in a laboratory, and it is different from suspicious treatments sold in stem cell clinics, which the US Food and Drug Administration did not adopt any of them). Diagnosis is usually preceded by Parkinson disease to the loss of neurons that produce dopamine, which is a chemical transmission responsible for movement and coordination. If a person appears on the signs of the disease, such as tremor in the hand or hardening in the muscles, it has lost between 60% and 80% of these neurons in a part of the brain that controls movement. Since the 1990s, the researchers imagine the use of stem cells to replace these lost neurons. It seems that they eventually discover the right set of signs that stimulate stem cells to switch to neurons that produce dopamine. Musk: “Neuralink” planted a brain system in a third patient. In addition, these two experiments, who together tested separate treatments on 18 patients, gave tips that these cells can work as he plants, simply implanted in the brain. The main purpose of both studies was to ensure the integrity of stem cells and the acceptance of the future and its effectiveness as treatment. So far, things are good. However, there was a simple warning: As the treatments used stem cells of a donor instead of relying on the patient’s cells (a method that could market more easily), the participants initially had to take immune inhibitors who prevented their bodies from treating, and some suffered light to medium side effects associated with medicine. A long -term treatment is that the cells are established in their surrounding environment, and it seems effective, even after patients have stopped taking immune hubs. After planting it, which is a relatively simple process in which millions of cells are carefully distributed into a part of the brain, young neurons must ripen and the right bonds with their neighbors before starting the release of dopamine. It takes a few months, but the hope is concluded that once this network is completed, these cells can remain effective for many years, and even the patient has always stayed alive. What we know about the effect of Corona on the brain using an image technique that shows the ends of the nerve cells relieved by dopamine that patients continue to produce more nervous spinner compared to the case before planting. Both research groups have also found promising evidence, although it was for the time being that this approach could improve motor symptoms, and perhaps the quality of the lives of some patients. Of course, more work is needed to prove the effectiveness of these treatments. Researchers need to confirm their safety in broader studies and understand whether these cells will remain functional in the long run, and that they can make a tangible difference in the lives of patients. Advanced tests, “Bluerock Therapics”, affiliated with “Bayer”, have obtained a stem cell technology license related to Parkinson disease of “memorial salon chaying”, and the third phase of testing her treatment began about 100 people. Several other previous studies are still testing other approaches to use stem cells in Parkinson disease. Eventually, Parkinson’s patients will have to decide whether they want these treatments. During the years the researchers took to reach this promising stage, better ways to deliver dopamines’ sects appeared to the brain or treated symptoms of movement associated with Parkinson disease using a deep stimulation of the brain. The president of “Bojin” wants pioneering medicine, but not at the expense of profitability, but it is an important and perhaps more important because of his promising abilities in the treatment of other brain diseases. Proof of the possibility of stem cell transplanting safe in the brain is a step towards the dream of the supreme researchers of designing treatments that exceed symptoms, and they can already recover the brain or even protect it from future damage. Fify Tabar, a neurosurgery and neurosurgery biology at the “Memorial Cereng” cancer for cancer, said: “It is a concept that parts of the brain can be restored to give it a new life and effectiveness, which opens the door to other neurological disorders.” Lorenz Stoder, director of the Memorial Celong Citner Center for Voice Cell Science, has shown that the design of these treatments is now the easy part, adding: “Things will go much faster than an engineering perspective.” But he warned that the understanding of the right way to apply these instruments, that is, to the supporting cell or the neuron that must be connected to the brain is still a challenge. There is a tremendous amount of work awaiting us, but this concept that has been proven must be an incentive to continue with the work, either at the level of basic biology or to pay stem cell treatments.