New hope for treating osteoporosis and rheumatoid patients

Researchers from the “D-Chie” and China Medical University have identified two genetics that can play a major role in the diagnosis and treatment of rheumatoid arthritis and osteoporosis, using modern analysis tools and machine learning algorithms to study genetic relationships associated with patients. Rheumatoid arthritis is a common disease as it estimates 17 million people around the world. It causes the cells of the immune system for the joints, leading to pain, swelling, cartilage erosion and bones, and osteoporosis often develop as a condition associated with arthritis, due to bone damage caused by immune attacks, and also due to the side effects of some medicines used in treatment. According to the study, the researchers, according to the study, published in the journal “APL Biongation”, found two basic genes: atxn2l and mmp14 playing an important role in the development of the two. ATXN2L -No is one of the most important factors in regulating programmed cell death and cellular interactions. The gene shares different cellular operations, including the regulation of cell death, as it plays a role in the mechanism of programmed cell death, which helps get rid of damaged or unnecessary cells. In some studies, ATXN2L is also associated with cases such as spinal muscle atrophy and certain types of neuropathy. Joint health and osteoporosis The imbalance in this gene leads to an increase in the death of bone cells, which contributes to the decline of joint health and osteoporosis. As far as MMP14 is concerned, it is the gene responsible for the production of enzymes known as ‘metallopotase’, which plays an important role in breach of proteins in the matrix, and the theine is responsible for the reform of tissues as it contributes to the reform of tissues by breaking and growing the cells in the external matrix. The researchers say that this gene plays a role in the wound healing process by regulating the reform of tissues, and is also needed to maintain the health of the joints and cartilage, and help to exercise and dissolve the tissue. The researchers also say that the increase in the death of the programmed cells in the bone formation cells plays the greatest role in the destruction of the joints and the increasing infections in rheumatoid arthritis. This process also leads to legality in the case of osteoporosis, hence the importance of managing the two diseases in an integrated way. Treatment of rheumatoid arthritis and researchers says atxn2L -no is responsible for regulating operations such as programmed cells, and when a defect occurs, the risk of rheumatoid arthritis and osteoporosis increases, while the MMP14 gene contributes to the construction of external tissues such as cartilage, which has a roll in the erosion of joint tissue Biotechnology instruments relied on to study a wide range of genetic data, and used machine -learning -algorithms to analyze big data, and discover the genes most associated with mechanisms of rheumatoid arthritis and osteoporosis. Analyzes indicate that these genes play a role in organizing immunity and bone metabolism. The researchers suggest its use as indicators for the diagnosis or treatment of rheumatoid arthritis and osteoporosis. Researchers plan to use the results as a starting point for the development of new treatment options. The researchers believe that future plans include experimental studies to verify the results, and to investigate how to target these genes to improve treatment results. Future research will include developing personal treatments using artificial intelligence and learning the machine to predict the most vulnerable patients.