Study: High levels of caffeine in blood protected from obesity and diabetes

A recent study said that the high level of caffeine in the blood can limit the amount of fat in the body and protect the risk of type 2 diabetes. The results of the study published in the ‘British Medical Magazine’ showed that the potential role of calorie -free caffeine drinks in reducing obesity risk risks and type 2 diabetes may be ‘more worthy to investigate’, the researchers said. The previously published research indicates that drinking 3-5 cups of coffee per day, which is a rich source of caffeine, is linked to a decrease in the risk of the second type of diabetes and cardiovascular disease. A medium-sized coffee cup contains about 70-150 mg of caffeine. But most of the research published so far is related to observational -based studies, which cannot determine reliable causal effects, due to other factors that are likely to be influential, and it is difficult to separate any specific effects of caffeine from other compounds containing caffeine and foods containing caffeine. To try to overcome these problems, the researchers used the random distribution technique to find out the effect of high levels of caffeine in the blood on body fats and long -term risks of type 2 diabetes, and main cardiovascular disease; Such as coronary artery diseases, stroke, heart failure and irregular heartbeat. Random distribution technique uses genetic variables to detect a specific risk factor, in this case caffeine levels in the blood, to obtain genetic evidence that supports a specific result. In this study, this evidence was the weight and risk of type 2 diabetes. The researchers looked at the role of two genetic variables commonly found in “CYP1A2” and “AHR” genes, while about 10,000 European descent people participated in 6 long -term studies. The “CYP1A2” and “AHR” genes are quickly associated with caffeine metabolism in the body. The effect of caffeine and people with genetic variables associated with the slow metabolism of caffeine drinks on average coffee, but they have higher levels of caffeine in their blood compared to the people who quickly turn it to reach or retain the levels of the stimulating effects. And the metabolism is the process by which the input of the body of food and drinking is converted to energy. The results of the analysis showed that the high levels of caffeine in the expected blood, associated with low weight (body mass index) and fat in the body. The high levels of caffeine in the blood genetically associated with a decrease in the risk of the second type of diabetes. The researchers then used the same technique to investigate the extent of caffeine’s effect on the risk of type 2 diabetes, which can be driven mainly by simultaneous weight loss. The results showed that weight loss to half (43%) led the effect of caffeine to the risk of type 2 diabetes. There was no strong relationship between the levels of caffeine in the expected genetic blood, and the risk of any of the results of the studied cardiovascular disease. The researchers acknowledged the presence of different restrictions on their findings, including the use of only genetic variables, and only the inclusion of people of European origin. But it is known that caffeine increases metabolism, increases fat burning and reduces appetite. It is estimated that the consumption of 100 mg per day increases energy consumption by about 100 calories per day, thus reducing the risk of obesity. The researchers believe that at least the reverse relationship between coffee consumption and the risk of the second type of diabetes can be explained. Also read: