Studying cellular deliveries

Many cells, including cancer cells, are known to secrete short RNAs in tiny vesicles, which then move inside other cells — potentially a form of cell-to-cell communication.

In an article recently published in Cell ReportsJames G. Patton, PhD, and colleagues studied how colon cancer cells can secrete long RNAs in carefully regulated ways.

The authors had previously demonstrated how short, secreted RNAs can help other cancer cells grow and spread. In their latest work, they show that longer RNAs that either do or do not code for proteins can be secreted by cancer cells in specific ways.